Estimating kinetic constants from single channel data
نویسندگان
چکیده
منابع مشابه
Kinetic time constants independent of previous single-channel activity suggest Markov gating for a large conductance Ca-activated K channel
Models for the gating of ion channels usually assume that the rate constants for leaving any given kinetic state are independent of previous channel activity. Although such discrete Markov models have been successful in describing channel gating, there is little direct evidence for the Markov assumption of time-invariant rate constants for constant conditions. This paper tests the Markov assump...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1983
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(83)84341-0